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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 65-year-old man presents to the internal medicine clinic with decreased exercise tolerance, lower extremity edema, and shortness of breath.
He has a history of diastolic dysfunction (ejection fraction of 60%) and hypertension; BP =
150/90 mm Hg, HR = 86 bpm.
Current medications include digoxin 125 mcg daily, furosemide 40 mg daily, enalapril 10 mg twice daily, aspirin 325 mg daily, and potassium 10 mEq twice daily. The digoxin concentration is 0.4 ng/mL.
After resolution of this exacerbation, which of the following should the pharmacotherapy specialist recommend to the internist regarding this patient's maintenance drug therapy?

A) Discontinue digoxin and add metoprolol.
B) Increase digoxin.
C) Discontinue digoxin and add amlodipine.
D) Increase furosemide.

2. A study is conducted comparing two antibiotics for the treatment of UTIs. The results after 7 days of therapy demonstrated that Drug A was superior to Drug B in eradicating bacteria from the urine and eliminating signs and symptoms of infections. The investigators concluded that Drug A was significantly superior to Drug B (p<0.05). In subsequent studies, however, the two drugs were equivalent in efficacy.
Which one of the following types of error apparently occurred in the first study?

A) Beta error
B) Regression to the mean
C) Type ||
D) Type |

3. The risk of methemoglobinemia is highest with the use of:

A) benzocaine 6% topical cream in a 25-year-old for pain associated with a sunburn.
B) benzocaine 10% oral gel in a 67-year-old for oral pain associated with ill-fitting dentures.
C) benzocaine 7.5% oral gel in an 18-month-old for oral pain associated with teething.
D) benzocaine 20% topical cream in a 42-year-old for pain associated with insect bites.

4. A 50-year-old woman experienced acute renal failure after receiving contrast dye for an imaging study. Her estimated creatinine clearance is now 20 mL/min. Her medications include:
* Piperacillin/tazobactam 4.5g intravenously every 8 hours
* Azithromycin 500 mg intravenously daily
* Famotidine 40 mg orally twice daily
* Enoxaparin 40 mg subcutaneously daily
* Metoprolol succinate 100 mg orally daily
Which drugs require dose reduction due to acute renal failure?

A) Piperacillin/tazobactam, azithromycin, and enoxaparin
B) Piperacillin/tazobactam, famotidine, and metoprolol succinate
C) Piperacillin/tazobactam, famotidine, and enoxaparin
D) All of her current medications

5. In which of the following scenarios should the error be reported to the Institute for Safe Medication Practices?

A) A patient receives a 30-day supply of a prescription written for twice daily dosing with only 30 tablets dispensed.
B) A pharmacy technician fills a prescription incorrectly with a "sound-alike" product, but the error is caught by the pharmacist before being dispensed to the patient.
C) A shipment of influenza vaccine was received by the pharmacy and was not placed in a refrigerator until the following day.
D) A patient complains to a pharmacy manager that she did not receive an iPLEDGE brochure when receiving isotretinoin.

Solutions: